Artichoke extract, which contains high concentrations of compounds contained in the plant, is also increasingly popular as a supplement. Artichokes are low in fat, high in fiber and packed with vitamins and minerals such as vitamin C, vitamin K, folate, phosphorus and magnesium. They are also one of the best sources of antioxidants. Artichoke extract can minimize total and “poor” LDL cholesterol while increasing “healthy” HDL cholesterol.